The Department of Pediatrics at the University of Yamanashi provides local, regional and international leadership in promoting childhood wellness and health, as well as elucidating some of the genetic and molecular mechanisms of disease pathogenesis, particularly malignant disorders. It includes groups of hematology/oncology, endocrinology, neurology, nephrology, and cardiology.
Profile of the Faculty Members
Biological analysis of leukemia cells
; associate professor
Analysis of chimeric gene products in leukemias, analysis of regulatory mechanisms of apoptosis in hematopoietic cells
; assistant professor
Diagnosis and treatment of pediatric kidney disease, radiological diagnosis of urinary tract anomaly.
Analysis of mechanisms of cell cycle control in leukemic cells
Pediatric neurology, cognitive neurophysiology
Analysis of glucose metabolism in type 1 diabetes
General Description of Research Activities (Themes)
This group conducts clinical research focusing on chemotherapy and hematopoietic stem cell transplantation for pediatric hematological and oncological diseases. Basic research on molecules involved in the growth and apoptosis of leukemic cells is also conducted.
The group of Pediatric neurology elucidates the mechanisms of higher cortical
functions and dysfunctions in normal children, adolescences, and developmental
disorders, particularly ADHD, and LD.
Pediatric Nephrology Group
Goal of the treatment for our patients ｉｓ primarily the complete recovery and secondly the improvement of long term prognosis of nephritis, CAKUT, and other nephrological diseases.
The group conducts research on intra-myocardial cell calcium dynamics using the cardiac arrest model in rats. It is also developing a new catheter intervention device. Clinical research on the comprehensive treatment for pediatric cardiomyopathy is carried out.
Pediatric endocrinology, diabetes and metabolic diseases:
All these fields are covered by Board-certified sub-specialists, including clinical and basic research on growth and sexual development, thyroid and adreal disorders, type 1 and 2 diabetes mellitus and metabolic syndrome according to patients' life cycles, especially focusing on children and adolescents
The Center for Genetic Medicine (http://www.genetcenter.com/index2.html)
Diagnosis for genetic disorders including congenital multiple anomalies.
Management of genetic disorders (Down syndrome, Prader-Willi syndrome, Marfan syndrome, and other genetic disorders).
Genetic counseling provided by clinical psychotherapist and Japanese-board of medical genetics-certified specialist physicians.
The group reveals the mechanism of children’s pulmonary disorder and investigates the mechanism of sleep disorder which includes sleep respiratory disorder in children, and develops a new non-invasive examination system of sleep disorder for children.