Kobayashi Y, Sakai K, Nguyen Quoc Vuong Tran, Ishimaru K, Sato T, Nakamura Y, Nakagomi D, Tanaka S, Koizumi S, Nakoa A: IL-33 sensitizes mast cells to Piezo1 stimulation leading to degranulation. Allergy 79(12):3517-3520, 2024
Nguyen Quoc Vuong Tran, Kobayashi Y, Nakamura Y, Ishimaru K, Izuhara K, Nakao A: Transcriptomic Evidence for T Cell-Fibroblast-Keratinocyte Axis via IL-13-Periostin-Integrin in Atopic Dermatitis Allergy 79(12):3521-3525, 2024
Nguyen Quoc Vuong Tran, Minh Khang Le, Nakamura Y, Nakao A: Severe asthmatic airways have distinct circadian clock gene expression pattern associated with WNT signaling Clinical and Translational Allergy 14(7):e12379, 2024
Nakamura Y, Urakami T, Ishimaru K, Nguyen Quoc Vuong Tran, Shimizu T, William Sinko, Takahashi T, Sivapriya Marappan, Kishore Narayanan, Ramulu Poddutoori, Terada Y, Nakao A: A highly selective KIT inhibitor MOD000001 suppresses IgE-mediated mast cell activation Journal of Allergy and Clinical Immunology: Global 3(3):100249, 2024
Nguyen Quoc Vuong Tran, Nakamura Y, Nakao A: Unique circadian clock gene expression pattern linked to WNT signaling in severe asthmatic airways. 第73回日本アレルギー学会学術大会 2024年10月18-20日 京都
Nguyen Quoc Vuong Tran, Nakao A, Nakamura Y: シンポジウム講演「A link between KIT expression, mast cell abundance and activity, and Th2-high endotype in asthmatic airways」 第73回日本アレルギー学会学術大会 2024年10月18-20日 京都
Nguyen Phuc Tan, Nakamura Y, Ishimaru K, Nguyen Thuy An, Tran Nguyen Quoc Vuong, Okuda T, Nakao A:
Ethyl caffeate can antagonize the aryl hydrocarbon receptor signaling,
which is associated with its anti-allergic property. 第72回アレルギー学会学術大会 2023年10月20-22日
東京
Nakamura Y, Nakao A:MOD000001, a Novel Highly Selective and Orally Available KIT Inhibitor, Suppresses Passive Cutaneous Anaphylactic (PCA) Reaction and Food Allergy in Mice. 2023 AAAAI Annual Meeting 2023年2月24-27日 San Antonio, USA
Nakamura Y, Nakao A, Shibata S: Inhibition of IgE-mediated allergic reaction by pharmacologically
targeting the circadian clock. 第45回日本免疫学会学術集会 2016年12月5-7日 沖縄
Le Pham Thu Ha, Nakamura Y, Nakao A: Migration of Th17 cells to the small intestine is temporally
regulated by the circadian clock. 第45回日本免疫学会学術集会 2016年12月5-7日 沖縄
中村勇規, 柴田重信, 中尾篤人:Regulation of plasma histamine levels by the mast cell clock
and its modulation by stress. 第23回日本時間生物学会学術大会 2016年11月12-13日 名古屋
Ihara T, Kira S, Miyamoto T, Sawada N, Nakagomi H, Mitsui T, Kobayashi
H, Yoshiyama M, Takeda M, Nakamura Y, Nakao A, Shigetomi E, Shibata K, Shinozaki Y, Koizumi S: Clock genes
regulate the circadian rhythm of Piezo1 and TRPV4 expressions and intracellular
Ca2+ influx after stretch stimulation in cultured urothelial cells. 31th
Annual Congress of the European Association of Urology Abstracts 2016年3月11-15日
Munich, Germany
Nakamura Y, Shibata S, Nakao A:Inhibition of IgE-Mediated Allergic Reaction By Pharmacologically
Targeting the Circadian Clock. 2016 AAAAI Annual Meeting 2016年3月4-7日 Los
Angeles
Nakamura Y:Circadian clock gene Period2 regulates a time-of-da-dependent variation
in cutaneous anaphylactic reaction. 2011 International joint meeting of
Bonn University, Waseda University, University of Yamanashi and Tokyo University
of Agriculture and Technology. 2011年6月14日 東京
中村勇規(翻訳):付録Ⅰ~Ⅲ 『アバス-リックマン-ピレ 分子細胞免疫学 原著第10版』 エルゼビア・ジャパン株式会社 p565-591, 2023 中尾篤人(監訳)[原著者:Abul
K.Abbas, Andrew H.Lichtman, Shiv Pillai 原著書名:Cellular and Molecular Immunology,
Tenth Edition]
中村勇規(翻訳):付録Ⅰ~Ⅲ 『アバス-リックマン-ピレ 分子細胞免疫学 原著第9版』 エルゼビア・ジャパン株式会社 p543-568, 2018 中尾篤人(監訳)[原著者:Abul
K.Abbas, Andrew H.Lichtman, Shiv Pillai 原著書名:Cellular and Molecular Immunology,
Ninth Edition]
翻訳書
2023
Nagasaka Y, Nakamura Y, Nguyen Quoc Vuong Tran, Kobayashi Y, Nakano N, Nakao A: Deficiency of BMAL1 promotes ROS generation and enhances IgE-dependent degranulation in mast cells. Biochem Biophys Res Commun 690:149295, 2023
Tran Nguyen Quoc Vuong, Le Minh Khang, Nakamura Y, Kondo T, Nakao A: A link between KIT expression, mast cell abundance
and activity, and Th2-high endotype in asthmatic airways Allergy 79(5):1338-1342 2023
Kobayashi Y, Suzuki K, Tateno M, Nakamura Y, Ishimaru K, Nagasaka Y, Sakurai D, Ohashi-Doi K, Nakao A:Cha o 3, a cypress
polle allergen, does not activate basophils in Japanese cypress pollinosis
J Allergy Clin Immun Global 3(1):100198, 2023
Phuc-Tan Nguyen, Nakamura Y , Nguyen Quoc Vuong Tran , Ishimaru K , Thuy-An Nguyen ,Kobayashi Y, Watanabe-Saito F, Okuda T, Nakano N ,Nakao A: Ethyl Caffeate Can Inhibit Aryl Hydrocarbon Receptor (AhR) Signaling and AhR-Mediated Potentiation of Mast Cell Activation. Int J Mol Sci 24(12), 9997, 2023
Matsushita K, Li X, Nakamura Y, Dong D, Mukai K, Tsai M, Montgomery SB, Galli SJ: The role of Sp140 revealed in IgE and mast cell responses in Collaborative Cross mice. JCI Insight 6(12):146572, 2021
2021
Nakamura Y, Ishimaru K, Nakao A: Time-restricted feeding in rest phase alters IgE/mast
cell–mediated allergic reaction in mice. Allergology International 69(2):296-299, 2020
2020
Huang Y, Zhang Z, Huang Y, Mao Z, Yang X, Nakamura Y, Sawada N, Mitsui T, Takeda M, Yao J: Induction of inactive TGF-β1 monomer formation by hydrogen sulfide contributes to its suppressive effects on Ang II- and TGF-β1-induced EMT in renal tubular epithelial cells. Biochem Biophys Res Commun 501(2)534-540, 2018
Ihara T, Mitsui T, Nakamura Y, Kanda M, Tsuchiya S, Kira S, Nakagomi H, Sawada N, Kamiyama M, Shigetomi E, Shinozaki Y, Yoshiyama M, Nakao A, Takeda M, Koizumi S: The time-dependent variation of ATP release in mouse primary-cultured urothelial cells is regulated by the clock gene. Neurourol Urodyn 37(8)2535-2543, 2018
Ihara T, Mitsui T, Nakamura Y, Kanda M, Tsuchiya S, Kira S, Nakagomi H, Sawada N, Kamiyama M, Hirayama Y, Shigetomi E, Shinozaki Y, Yoshiyama M, Nakao A, Takeda M, Koizumi S: The oscillation of intracellular Ca2+ influx associated with the circadian expression of Piezo1 and TRPV4
in the bladder urothelium. Scientific Reports 8(1)5699, 2018
Matsuzawa T, Nakamura Y, Ogawa Y, Ishimaru K, Goshima F, Shimada S, Nakao A, Kawamura T: Differential
Day–Night Outcome to HSV-2 Cutaneous Infection. Journal of Investigative Dermatology 138(1)233-236, 2018
Ihara T, Mitsui T, Nakamura Y, Kanda M, Tsuchiya S, Kira S, Nakagomi H, Sawada N, Hirayama Y, Shibata
K, Shigetomi E, Shinozaki Y, Yoshiyama M, Nakao A, Takeda M, Koizumi S:
The Circadian expression of Piezo1, TRPV4, Connexin26, and VNUT, associated
with the expression levels of the clock genes in mouse primary cultured
urothelial cells. Neurourol Urodyn 37(3)942-951, 2018
2018
Thu Le HP, Nakamura Y, Oh-oka K, Ishimaru K, Nakajima S, Nakao A: The frequency of Th17 cells
in the small intestine exhibits a dayenight variation dependent on circadian
clock activity. Biochem Biophys Res Commun 490(2)290-295, 2017
Ihara T, Mitsui T, Kira S, Miyamoto T, Sawada N, Nakagomi H, Yoshiyama
M, Takeda M, Nakamura Y, Nakao A, Shinozaki Y, Koizumi S: The Clock mutant mouse is a novel experimental
model for nocturia and nocturnal polyuria. Neurourology and Urodynamics 36(4)1034-1038, 2017
Kawauchi T, Ishimaru K, Nakamura Y, Nakano N, Hara M, Ogawa H, Okumura K, Shibata S, Nakao A: <i>Clock</i>-dependent
temporal regulation of IL-33/ST2-mediated mast cell response. Allergology International 66(3)472-478, 2017
Nakamura Y, Ishimaru K, Shibata S, Nakao A: Regulation of plasma histamine levels
by the mast cell clock and its modulation by stress. Scientific Reports 7 Article number:39934, 2017
Ihara T, Mitsui T, Nakamura Y, Kira S, Nakagomi H, Sawada N, Hirayama Y, Shibata K, Shigetomi E, Shinozaki Y, Yoshiyama M, Andersson KE, Nakao A, Takeda M, Koizumi S: Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa. PLoS One 12(1):e0168234, 2017
2017
Igarashi S, Suzuki K, Nakamura Y, Ishimaru K, Fukano C, Masuyama K, Ohashi-Doi K, Nakao A: The efficacy
of sublingual immunotherapy for allergic rhinitis may vary with the time
of day. Int Arch Allergy Immunol 171(2)111-118, 2016
Nakamura Y, Nakano N, Ishimaru K, Ando N, Katoh R, Suzuki-Inoue K, Koyanagki S, Ogawa
H, Okumura K, Shibata S, Nakao A: Inhibition of IgE-mediated allergic reaction
by pharmacologically targeting the circadian clock. J Allergy Clin Immun 137(4)1226-1235, 2016
2016
Ando N, Nakamura Y, Aoki R, Ishimaru K, Ogawa H, Okumura K, Shibata S, Shimada S, Nakao A:
Circadian Gene Clock Regulates Psoriasis-like Skin Inflammation in Mice. Journal of Investigative Dermatology 135:3001-3008, 2015
Nakao A, Nakamura Y, and Shibata S: The Circadian Clock Functions As A Potent Regulator of
Allergic Reaction. [Review] Allergy 70(5)467-473, 2015
Ando N, Nakamura Y, Ishimaru K, Ogawa H, Okumura K, Shimada S, and Nakao A: Allergen-specific
basophil reactivity exhibits daily variations in seasonal allergic rhinitis.
Allergy 70(3)319-322, 2015
2015
Nakamura Y*, Ishimaru K*, Tahara Y*, Shibata S, Nakao A: Disruption of the Suprachiasmatic Nucleus Blunts A Time of Day-Dependent Variation in Systemic Anaphylactic Reaction in Mice. Journal of Immunology Research vol.2014 Article ID474217, 2014 (*Thease authers contributed equally to this work.)
Fukumoto S, Toshimitsu T, Matsuoka S, Maruyama A, Oh-oka K, Takamura T,
Nakamura Y, Ishimaru K, Fujii-Kuriyama Y, Ikegami S, Itou H, Nakao A:Identification
of a probiotic bacteria-derived activator of the aryl hydrocarbon receptor
that inhibits colitis. Immunology and Cell Biology 92(5)460-465, 2014
Nakamura Y, Nakano N, Ishimaru K, Hara M, Ikegami T, Tahara Y, Katoh R, Ogawa H,
Okumura K, Shibata S, Nishiyama C, and Nakao A: Circadian regulation of
allergic reaction by the mast cell clock in mice. J Allergy Clin Immun 133(2)568-575.e12, 2014
2014
Zhu Y, Ohba T, Ando T, Fujita K, Koyama K, Nakamura Y, Katoh R, Haro H, Nakao A: Endogenous TGF-β activity limits TSLP expression
in the intervertebral disc tissue by suppressing NF-κB activation. J Orthop Res 31(7)1144-1149, 2013
Takita E, Yokota S, Tahara Y, Hirao A, Aoki N, Nakamura Y, Nakao A, Shibata S: Biological clock dysfunction exacerbates contact
hypersensitivity in mice. Brit J Dermatol 168(1)39-46, 2013
2013
Nakamura Y, Harama D, Shimokawa N, Hara M, Suzuki R, Tahara Y, Ishimaru K, Katoh
R, Okumura K, Ogawa H, Shibata S, Nakao A: Circadian clock gene Period2
regulates a time-of-day-dependent variation in cutanenous anaphylactic
reaction. J Allergy Clin Immun 127(4)1038-1045, 2011
Takamura T, Harama D, Fukumoto S, Nakamura Y, Shimokawa N, Ishimaru K, Ikegami S, Makino S, Kitamura M, Nakao A: Lactobacillus
bulgaricus OLL1181 activates the aryl hydrocarbon receptor pathway and
inhibits colitis. Immunology and Cell Biology 89(7)817-822, 2011
2011
Okada Y, Oh-oka K, Nakamura Y, Ishimaru K, Matsuoka S, Okumura K, Ogawa H, Hisamoto M, Okuda T, Nakao
A: Dietary Resveratrol Prevents the Development of Food Allergy in Mice.
PLoS One 7(9)e44338, 2012
2012
Takamura T, Harama D, Matsuoka S, Shimokawa N, <B>Nakamura Y</B>,
Okumura K, Ogawa H, Kitamura M, Nakao A: Activation of the aryl hydrocarbon
receptor pathway may ameliorate dextran sodium sulfate-induced colitis
in mice. Immunology and Cell Biology 88(6)685-689, 2010
2010
Miyata M, Nakamura Y, Shimokawa N, Ohnuma Y, Katoh R, Matsuoka S, Okumura K, Ogawa H, Masuyama
K, Nakao A: Thymic stromal lymphopoietin is a critical mediator of IL-13-driven
allergic inflammation. Eur J Immunol 39(11)3078-3083, 2009
Nakamura Y, Miyata M, Ando T, Shimokawa N, Ohnuma Y, Katoh R, Ogawa H, Okumura K,
Nakao A: The latent form of transforming growth factor-β administered orally
is activated by gastric acid in mice. J Nutr 139(8)1463-1468, 2009
Nakamura Y, Miyata M, Shimokawa N,Ohnuma Y, Katoh R, Ogawa H, Okumura K, Nakao A:
House dust mite allergen Der f 1 can induce the activation of latent TGF-β
via its protease activity. FEBS Letters 583(12)2088-2092,2009
Harama D, Koyama K, Mukai M, Shimokawa N, Miyata M, Nakamura Y, Ohnuma Y, Ogawa H, Matsuoka S, Paton AW, Paton JC, Kitamura M, Nakao
A: A sub-cytotoxic dose of subtilase cytotoxin prevents LPS-induced inflammatory
responses, depending on its capacity to induce the unfolded protein response.
J Immunol 183(2)1368-1374, 2009
2009
Nakamura Y, Miyata M, Ohba T, Ando T, Hatsushika K, Suenaga F, Shimokawa N, Ohnuma
Y, Katoh R, Ogawa H, Nakao A: Cigarette smoke extract induces thymic stromal
lymphopoietin expression, leading to TH2-type immune responses and airway
inflammation. J Allergy Clin Immun 122(6)1208-1214, 2008
Ohba T, Haro H, Ando T, Koyama K, Hatsushika K, Suenaga F, Ohnuma Y, Nakamura Y, Katoh R, Ogawa H, Hamada Y, Nakao A: A potential role of TSLP in the recruitment of macrophages to the intervertebral disc via MCP-1 induction:The implications in a herniated discs. Arthritis and Rheumatism 58(11)3510-3519, 2008
2008
Nakao A, Nakamura Y: Time will tell about mast cells: Circadian control of mast cell activation. Allergology International 71(4):425-431, 2022
2022
Ishimaru K, Nakajima S, Yu G, Nakamura Y, Nakao A: The Putatively Specific Synthetic REV-ERB Agonist SR9009 Inhibits IgE- and IL-33-Mediated Mast Cell Activation Independently of the Circadian Clock. Int J Mol Sci 20(24)6320, 2019
Nakajima S,Ishimaru K, Kobayashi A, Guannan Yu, Nakamura Y, Oh-oka K, Suzuki-Inoue K, Kono K, Nakao A: Resveratrol inhibits IL-33–mediated
mast cell activation by targeting the MK2/3–PI3K/Akt axis. Sci Rep 9(1):18423, 2019
Nakamura Y, Sasaki T, Mochizuki C, Ishimaru K, Koizumi S, Shinmori H, Suzuki-Inoue
K, Nakao A: Snake venom rhodocytin induces plasma extravasation via toxin-mediated
interactions between platelets and mast cells. Sci Rep 9(1):15958, 2019
Ihara T, Nakamura Y, Mitsui T, Tsuchiya S, Kanda M, Kira S, Nakagomi H, Sawada N, Kamiyama M, Shigetomi E, Shinozaki Y, Yoshiyama M, Nakao A, Koizumi S, Takeda M: Intermittent restraint stress induces circadian misalignment in the mouse bladder, leading to nocturia. Sci Rep 9(1):10069, 2019
2022. 2.26 第2回SLDDDRS-UHCT-A Webinar: New Biology of Mast Cells 講演「S. Venezuelensis Egg Clearance in Primary Infections shows a Time-of-day-dependent Variation in Mice」