Shinozaki Y, Leung A, Namekata K, Saitoh S, Nguyen HB, Takeda A, Danjo Y, Morizawa YM, Shigetomi E, Sano F, Yoshioka N, Takebayashi H, Ohno N, Segawa T, Miyake K, Kashiwagi K, Harada T, Ohnuma S, Koizumi S. (2022) Astrocytic dysfunction induced by ABCA1 deficiency causes optic neuropathy. Sci Adv, 8(44):eabq1081. doi: 10.1126/sciadv.abq1081. Epub 2022 Nov 4.
Yokoyama T, Kuga T, Itoh Y, Otake S, Omata C, Saitoh M, Miyazawa K: Smad2Δexon3 and Smad3 have distinct properties in signal transmission leading to TGF-β-induced cell motility. J Biol Chem. 299:102820, 2023(2月)
Itoh Y, Sawaguchi T, Fu H, Omata C, Saitoh M, Miyazawa K: Indole-derived compound SIS3 targets a subset of activated Smad complexes. J Biochem. 173:283-291, 2023 (3月31日)
2021年
Danjo Y, Shigetomi E, Hirayama YJ, Kobayashi K, Ishikawa T, Fukazawa Y, Shibata K, Takanashi K, Parajuli B, Shinozaki Y, Kim SK, Nabekura J and *Koizumi S:Transient astrocytic mGluR5 expression drives synaptic plasticity and subsequent chronic pain in mice.J Exp Med, 219 (4): e20210989, 2022
Danjo Y, Shinozaki Y, Natsubori A, Kubota Y, Kashiwagi K, Tanaka KF and *Koizumi S: The Mlc1 promotor directs Müller cell-specific gene expression in the retina. TVST, 11(1), 25. doi: 10.1167/tvst.11.1.25, 2022
Tanaka M, Shigetomi E, Parajuli B, Nagatomo H, Shinozaki Y, Hirayama Y, Saito K, Kubota Y, Danjo Y, Lee JH, Kim SK, Nabekura J, Koizumi S: Adenosine A2B Receptor down-regulates Metabotropic Glutamate Receptor 5 in astrocytes during postnatal development. GLIA, 69(11):2546-2558. doi: 10.1002/glia.24006. Epub 2021 Aug 2, 2021
Kinoshita M, Ogawa Y, Hama N, Ujiie I, Hasegawa A, Nakajima S, Nomura T, Adachi J, Sato T, Koizumi S, Shimada S, Fujita Y, Takahashi H, Mizukawa Y, Tomonaga T, Nagao K, Abe R, Kawamura T. Neutrophils initiate and exacerbate Stevens-Johnson syndrome and toxic epidermal necrolysis. Sci Transl Med. 2021
Okubo A, Uchida Y, Higashi Y, Sato T, Ogawa Y, Ryuge A, Kadomatsu K, Kanekura T. CD147 Is Essential for the Development of Psoriasis via the Induction of Th17 Cell Differentiation. Int J Mol Sci. 2021
Shiokawa I, Sato T (equal first author), Ogawa Y, Nagasaka Y, Ishikawa A, Shimada S, Kawamura T, Momosawa A. Tissue Expander-associated T Cells: Relevance to Breast Implant-associated Anaplastic Large-cell Lymphoma.Plast Reconstr Surg Glob Open.10(3):e4148.doi:10.1097, 2022
Suzuki T, Hirai Y, Uehara T, Ohga R, Kosaki K, Kawahara A: Involvement of the zebrafish trrap gene in craniofacial development. Scientific Reports. 11: 24166, 2021
2020年
Sone R, Taimatsu K, Ohga R, Nishimura T, Tanaka M, Kawahara A: Critical roles of the ddx5 gene in zebrafish sex differentiation and oocyte maturation. Scientific Reports 10: 14157, 2020
Kawamura M, Tamada D, Funayama S, Kromrey ML, Ichikawa S, Onishi H, Motosugi U:Accelerated Acquisition of High-resolution Diffusion-weighted Imaging of the Brain with a Multi-shot Echo-planar Sequence: Deep-learning-based Denoising. Magn Reson Med Sci, 20 (1): 99-105. 2021.
Itoh Y, Koinuma D, Omata C, Ogami T, Motizuki M, Yaguchi SI, Itoh T, Miyake K, Tsutsumi S, Aburatani H, Saitoh M, Miyazono K, Miyazawa K: A comparative analysis of Smad-responsive motifs identifies multiple regulatory inputs for TGF-β transcriptional activation. J Biol Chem. 294: 15466-15479, 2019
Kume A, Kashiwagi K : Recent Epidemiological Status of Ocular and Other Major Complications Related to Diabetes Mellitus in Japan Ophthalmologica Online ahead of print, 2020
Ogawa Y*, Kinoshita M, Sato T, Shimada, Kawamura T : Biotin is required for the zinc homeostasis in the skin. Nutrients. 11(4):E919, 2019
Suzuki H, Ishizaka T, Yanagi K, Sone R, Ohga R, Kawahara A : Characterization of biklf/klf17-deficient zebrafish in posterior lateral lineneuromast and hatching gland development . Scientific Reports 9, 13680 (2019)
Yanagi K, Sone R, Ohga R, Kawahara A : Involvement of the centrosomal protein 55 (cep55) gene in zebrafish head formationGenes to Cells 24, 642-649 (2019)
2018年
Kawahara A, Morita H, Yanagi K, Suzuki H, Mori T, Ohga R, Taimatsu K : Spatiotemporal expression of the cocaine- and amphetamine-regulated transcript-like (cart-like) gene during zebrafish embryogenesis .Gene Expression Patterns 30, 1-6 (2018)
Shamoto N, Narita K, Kubo T, Oda T, Takeda T: CFAP70 Is a Novel Axoneme-Binding Protein That Localizes at the Base of the Outer Dynein Arm and Regulates Ciliary Motility. Cells.7(9) , 124;doi:10.3390/cells7090124, 2018
Tsukiji N, Osada M, Sasaki T, Shirai T, Satoh K,Inoue O, Umetani N, Mochizuki C, Saito T, Kojima S, Shinmori H, Ozaki Y, Suzuki-Inoue K:Cobalt hematoporphyrin inhibits CLEC-2–podoplanin interaction, tumor metastasis, and arterial/venous thrombosis in mice. Blood Advances 2:2214-2225;2018 https://www.ncbi.nlm.nih.gov/pubmed/30190281
Johno H, Yoshimura K, Mori Y, Kimura T, Niimi M, Yamada M, Tanigawa T, Fan J, Takeda S: Detection of potential new biomarkers of atherosclerosis by probe electrospray ionization mass spectrometry. Metabolomics. 14:38, 2018
2017年
Kikushima W, Sakurada Y, Sugiyama A, Tanabe N, Kume A, Iijima H: Comparison of initial treatment between 3-monthly intravitreal aflibercept monotherapy and combined photodynamic therapy with single intravitreal aflibercept for polypoidal choroidal vasculopathy. Graefes Arch Clin Exp Ophthalmol. 255(2):311-316, 2017
Sakurada Y, Sugiyama A, Tanabe N, Kikushima W, Kume A, Iijima H: CHOROIDAL THICKNESS AS A PROGNOSTIC FACTOR OF PHOTODYNAMIC THERAPY WITH AFLIBERCEPT OR RANIBIZUMAB FOR POLYPOIDAL CHOROIDAL VASCULOPATHY. Retina. 37(10):1866-1872, 2017
Kikushima W, Sakurada Y, Yoneyama S, Sugiyama A, Tanabe N, Kume A, Mabuchi F: Iijima H. Incidence and risk factors of retreatment after three-monthly aflibercept therapy for exudative age-related macular degeneration. Sci Rep.7;7:44020, 2017
Kasai S, Furuichi Y, Ando N, Kagami K, Abe M, Nakane T, Goi K, Inukai T, Saitoh S, Ohno S, Okazaki S, Nagano O, Saya H, Sugita K: Inflammatory mediator ultra-low-molecular-weight hyaluronan triggers necrosis of B-precursor leukemia cells with high surface CD44 expression. Cell Death Dis. 1;8(6):e2857 ,2017
Zhang J, Niimi M, Yang D, Liang J, Xu J, Kimura T, Mathew AV, Guo Y, Fan Y, Zhu T, Song J, Ackermann R, Koike Y, Schwendeman A, Lai L, Pennathur S, Garcia-Barrio M, Fan J, Chen YE: Deficiency of cholesteryl ester transfer protein protects against atherosclerosis in rabbits. Arterioscler Thromb Vasc Biol. 37(6):1068-1075,2017
Amano R, Yamashita A, Kasai H, Hori T, Miyasato S, Saito S, Tsubuki M, Moriishi K: Catechol group of cinnamic acid derivative is essential for its anti-hepatitis C virus activity. Yamanashi Medical Journal, 32: 95 – 103, 2017
Furuya S, Endo K, Takahashi A, Miyazawa K, and Saitoh M: Snail suppresses cellular senescence and promotes fibroblast-led cancer cell invasion. FEBS Open Bio. 7: 1586-1597, 2017
Yamazaki C, Tamaoki T, Nunomura A, Tamai K, Yasuda K, and Motohashi N: Plasma Amyloid-β and Alzheimer’s Disease-Related Changes in Late-Life Depression. J Alzheimer’s Dis 58: 349-354, 2017 https://www.ncbi.nlm.nih.gov/pubmed/28453490
2016年
Ota S, Taimatsu K, Yanagi K, Namiki T, Ohga R, Higashijima S, and Kawahara A: Functional visualization and disruption of targeted genes using CRISPR/Cas9-mediated eGFP reporter integration in zebrafish.Sci Rep 6: 34991, 2016
Kume A, Ohshiro T, Sakurada Y, Kikushima W, Yoneyama S, and Kashiwagi K: Treatment Patterns and Health Care Costs for Age-Related Macular Degeneration in Japan: An Analysis of National Insurance Claims Data. Ophthalmology 123: 1263-1268, 2016
Saitoh M, Endo K, Furuya S, Minami M, Fukasawa A, Imamura T, and Miyazawa K: STAT3 integrates cooperative Ras and TGF-β signals that induce Snail expression. Oncogene 35: 1049-1057, 2016
Hoshi Y, Endo K, Shirakihara T, Fukagawa A, Miyazawa K, and Saitoh M: The potential role of regulator of G-protein signaling 16 (RGS16) in cell motility mediated by δEF1 family proteins. FEBS Lett 590: 270-278, 2016
Taguchi M, Shinozaki Y, Kashiwagi K, Shigetomi E, Robaye B, and Koizumi S: Müller cell-mediated neurite outgrowth of the retinal ganglion cells via P2Y6 receptor signals. J Neurochem 136: 741-751, 2016
2015年
Mano Y, Yokomichi H, Suzuki K, Takahashi A, Yoda Y, Tsuji M, Sato M, Shinohara R, Mizorogi S, Mochizuki M, Yamagata Z: Do body mass index trajectories affect the risk of type 2 diabetes? A case-control study. BMC Public Health 15:718, 2015
Maeyama H, Hirasawa T, Tahara Y, Obata C, Kasai H, Moriishi K, Mochizuki K, and Kubota T: Maternal restraint stress during pregnancy in mice induces 11β-HSD1-associated metabolic changes in the livers of the offspring. J Dev Orig Health Dis 24: 1-10, 2015
Fukagawa A, Ishii H, Miyazawa K, and Saitoh M: δEF1 associates with DNMT1 and maintains DNA methylation of the E-cadherin promoter in breast cancer cells. Cancer Med 4: 125-135, 2015
2014年
Yoshimura K, Chen LC, Johno H, Nakajima M, Hiraoka K, and Takeda S: Development of Non-proximate Probe Electrospray Ionization for Real-Time Analysis of Living Animal. Mass Spectrom 3: SO048, 2014
Fukumoto S, Toshimitsu T, Matsuoka S, Maruyama A, Oh-oka K, TakamuraT, Nakamura Y, Ishimaru K, Fujii-Kuriyama Y, Ikegami S, Itou H, and Nakao A: Identification of a probiotic bacteria-derived activator of the aryl hydrocarbon receptor that inhibits colitis. Immunol Cell Biol 92: 460-465, 2014
Furuta J, Inozume T, Harada K, and Shimada S: CD271 on melanoma cell is an IFN-g-inducible immunosuppressive factor that mediates downregulation of melanoma antigens. J Invest Dermatol 134: 1369-1377, 2014
2013年
Shirakihara T, Kawasaki T, Fukagawa A, Semba K, Sakai R, Miyazono K, Miyazawa K, and Saitoh M: Identification of integrin α3 as a molecular marker of cells undergoing EMT and of cancer cells with aggressive phenotypes.Cancer Sci 104: 1189-1197, 2013
Noguchi Y, Shinozaki Y, Fujishita K, Shibata K, Imura Y, Morizawa Y, Gachet C, and Koizumi S: Astrocytes protect neurons against methylmercury via ATP/P2Y1 receptor-mediated pathways in astrocytes. PLoS One 8: e57898, 2013
Kinoshita M, Nasu-Tada K, Fujishita K, Sato K, and Koizumi S: Secretion of matrix metalloproteinase-9 from astrocytes by inhibition of tonic P2Y14 receptor-mediated signal(s). Cell Mol Neurobiol 33: 47-58, 2013
2011年
Nakamura Y, Harama D, Shimokawa N, Hara M, Suzuki R, Tahara Y, Ishimaru K, Katoh R, Okumura K, Ogawa H, Shibata S, and Nakao A: The circadian clock gene Period2 regulates a time of day-dependent variation in cutanenous anaphylactic reaction. J Allergy Clin Immunol 127: 1038-1045, 2011
Takamura T, Harama D, Fukumoto S, Nakamura Y, Shimokawa N, Ohshima K, Ikegami S, Makino S, Kitamura M, and Nakao A: Lactobacillus bulgaricus OLL1181 activates the aryl hydrocarbon receptor pathway and inhibits colitis. Immunol Cell Biol 89: 817-822, 2011
2010年
Takamura T, Harama D, Matsuoka S, Shimokawa N, Nakamura Y, Okumura K, Ogawa H, Kitamura M, and Nakao A: Activation of the aryl hydrocarbon receptor pathway may ameliorate dextran sodium sulfate-induced colitis in mice. Immunol Cell Biol 88: 685-689, 2010
2009年
Harama D, Koyama K, Mukai M, Shimokawa N, Miyata M, Nakamura Y, Ohnuma Y, Ogawa H, Matsuoka S, Paton AW, Paton JC, Kitamura M, and Nakao A: A sub-cytotoxic dose of subtilase cytotoxin prevents LPS-induced inflammatory responses, depending on its capacity to induce the unfolded protein response. J Immunol 183: 1368-1374, 2009
Koike T, Kitajima S, Yu Y, Li Y, Nishijima K, Liu E, Sun H, Waqar AB, Shibata N, Inoue T, Wang Y, Zhang B, Kobayashi J, Morimoto M, Saku K, Watanabe T, and Fan J: Expression of human apoAII in transgenic rabbits leads to dyslipidemia: a new model for combined hyperlipidemia. Arterioscler Thromb Vasc Biol 29: 2047-2053, 2009